MICROBIOLOGY (MCRO)

Required preparation, one semester of a basic undergraduate science class. An introductory course in microbiology that focuses on the structure, biology, and genetics of microbes in relation to human disease and the immune system. For students planning careers in pharmacy, nursing, dental hygiene, and related fields. A laboratory is required.

Permission required. Experience includes preparations, demonstrations, assistance, and attendance at weekly meetings. Apprentices will not be involved in any aspects of grading.

Permission required. Experience includes preparations, demonstrations, assistance, and attendance in weekly meetings.

This course provides a general overview of the evolution, organization, and function of the immune system. Instruction will be inquiry-based with extensive use of informational and instructional technology tools.

A strong background in molecular biology, eukaryotic genetics, and biochemistry is required. Advanced survey course with topics that include molecular recognition, genetic mechanisms of host resistance, development of cells and cell interactions; hypersensitivity, autoimmunity, and resistance to infection. Course material from textbook and primary literature.

Required preparation, coursework in molecular biology and cell biology. Current concepts of the chemistry, structure, replication, genetics, and the natural history of animal viruses and their host cells.

This course explores cutting edge research in molecular biology -- the investigation at molecule-scale of the mechanisms behind life. We briefly review core-principles in molecular biology, then investigate more recent research that extends or overturns these core principles.

Required preparation for undergraduates, at least one undergraduate course in both biochemistry and genetics. The purpose of this course is to provide historical, basic, and current information about the flow and regulation of genetic information from DNA to RNA in a variety of biological systems. Three lecture hours a week.

Permission of the instructor. Required preparation, coursework in molecular biology and genetics. Topics will include aspects of basic bacteriology as well as bacterial and fungal pathogens and mechanisms of disease.

This course is intended to provide graduate students and advanced undergraduates with a broad survey of vector-borne diseases and an understanding of how pathogens interact with arthropod vectors. While this course will not be highly technical in nature or require deep knowledge of microbiology and/or immunology, students are expected to have some prior understanding of the fundamentals of biology in general (including cell/molecular biology, ecology, and evolution) and genetics in particular.

Permission of the instructor or a fundamental understanding of molecular virology and immunology. Molecular pathogenesis, with a primary focus on viral pathogens. Additional topics include vaccines and genetics of host-pathogen interactions.

Permission of the department except for department majors. Designed to introduce the student to research methods. Minor investigative problems are conducted with advice and guidance of the staff. Hours and credit to be arranged, any term. May be repeated for credit two or more semesters.

Faculty and student seminars on current research in microbiology and immunology.

Seminar on selected topics in microbiology.

This is an introductory course focused on methods to visualize scientific data and molecular structures and to use machine learning for big data exploration to solve relevant research questions. The course will include: R to visualize various biomedical data and generate multiple publication-ready figures and tables, phylogenetic analysis using R and other tools, and PyMol to visualize and analyze molecular structures and create images for publication. This course will also include a large codebase on using R and machine learning; introduce state-of-art packages to summarize and visualize various data types and to use machine learning for big data.

Approval from the course instructor required -- Knowledge of introductory biochemistry and molecular biology is required -- Previous experiences with R, PyMol, and machine learning are NOT necessary for attending this class. This is an introductory course focused on methods to visualize scientific data and molecular structures and to use machine learning for big data exploration to solve relevant research questions. The course will include: R to visualize various biomedical data and generate multiple publication-ready figures and tables, phylogenetic analysis using R and other tools, and PyMol to visualize and analyze molecular structures and create images for publication. This course will also include a large codebase on using R and machine learning; introduce state-of-art packages to summarize and visualize various data types and to use machine learning for big data.

This course is focused on introducing statistical modeling and modern visualization techniques for biological data using R. It begins with foundational statistical methods (linear and logistic regression) and their visualization, then moves into approaches for analyzing and visualizing both continuous and categorical data. Building on these fundamentals, the course emphasizes visualization of specialized biological data types, including phylogenetic trees, RNA sequencing (bulk RNAseq), protein structures, and single-cell RNAseq data. Students will learn how to apply computational tools to interpret complex biological datasets in a clear, visual format.

Permission of instructor -- Knowledge of introductory biochemistry and molecular biology is required -- Previous experiences with R, PyMol, and machine learning are NOT necessary for attending this class. This is an introductory course for biomedical graduate students and scientists focused on the use of machine learning/big data exploration to solve relevant research questions. The course will include: (a) Principles of machine learning in biomedical research (b) Introduction of supervised machine learning approach (c) Big data analysis, RNAseq and Olink proteomics, and (d) Prediction of protein structures using a machine learning approach, and evaluation and analysis of the predicted protein structures. This course will include a large codebase using R in machine learning and introduce state-of-the-art packages in machine learning. The instructors will use real biomedical research cases.

One or two faculty and a small number of students will consider current research of importance in depth. Emphasis is on current literature, invited speakers, etc., rather than textbooks.

One or two faculty and a small number of students consider current research of importance in depth. Emphasis is on current literature, invited speakers, etc., rather than textbooks.

One or two faculty and a small number of students consider current research of importance in depth. Emphasis is on current literature, invited speakers, etc., rather than textbooks.

MCRO 721 is a modular course that meets the requirements of the National Institutes of Health for refresher training in the Responsible Conduct of Research. The course involves a mixture of assigned readings, formal presentations by department faculty who are active in research, and small group discussions. The course grade is based on attendance and participation.

The goal of this graduate-level course is to learn about recent advances in the field, acquire specialized knowledge and to develop a foundation of critical thinking skills in cancer immunology and immunoengineering. This course will cover new advances in using engineering approaches for modulating immune systems, including nanovaccines, microneedle devices, cancer immunotherapy antibody therapy and immunosurveillance. The course format will combine lectures and in-class discussion of assigned readings, with particular emphasis on state-of-the art research methods. Students should be familiar with modern concepts of immunology and should consult with the course director before enrolling.

Students are expected to have taken MCRO 614 -- alternatively, students should be familiar with modern concepts of immunology and should consult with the course director before enrolling -- basic immunology course recommended but not required (for example, MCRO 449: Introduction to Immunology, MCRO 614: Immunobiology, or other relevant coursework). The goal of this graduate-level course is to learn about recent advances in the field, acquire specialized knowledge and to develop a foundation of critical thinking skills in tumor microenvironment, stroma, and immune compartment. The course format will combine lectures and in-class discussion of assigned readings, with particular emphasis on state-of-the art research methods. Students are expected to have taken MCRO 614; alternatively, students should be familiar with modern concepts of immunology and should consult with the course director before enrolling.

The goal of this graduate-level course is to learn about recent advances in the field, acquire specialized knowledge and to develop a foundation of critical thinking skills in cancer immunology. The course format will combine lectures and in-class discussion of assigned readings, with particular emphasis on state-of-the art research methods. Students should be familiar with modern concepts of immunology (e.g., understand content from MCRO 614 or equivalent; consult course director before enrolling) and should enroll in both MCRO 731/732.

This is a semester-long (3 credit) course whose requirements are fulfilled by completing any 3 1-credit MCRO courses during the same semester. The intended audience for this course is students enrolled in the M&I Special Masters program; enrollment in MCRO 740 requires permission of the course director. May be repeated for credit.

Designed to introduce the student to special topics in microbiology and immunology. Special topics may focus on a common scientific or disease mechanism, set of scientific techniques, cutting-edge scientific methods, or other designated area of focus. Enrollment in MCRO 741 requires permission of the course director. May be repeated for credit.

Designed to introduce the student to special topics in microbiology and immunology. Special topics may focus on a common scientific or disease mechanism, set of scientific techniques, cutting-edge scientific methods, or other designated area of focus. Enrollment in MCRO 742 requires permission of the course director. May be repeated for credit.

Designed to introduce the student to special topics in microbiology and immunology. Special topics may focus on a common scientific or disease mechanism, set of scientific techniques, cutting-edge scientific methods, or other designated area of focus. Enrollment in MCRO 743 requires permission of the course director. May be repeated for credit.

This course will cover new advances in using engineering approaches for modulating immune systems, including nanovaccines, microneedle devices, cancer immunotherapy antibody therapy and immunosurveillance. Basic immunology course is recommended but not required (e.g., MCRO 449: Introduction to Immunology, MCRO 614: Immunobiology, or other relevant coursework).

Permission of the instructor or one prior prokaryotic molecular biology course. Directed readings in prokaryotic molecular biology under the direction of a member of the graduate faculty. May be repeated for credit.

Permission of the instructor or one prior virology course. Directed readings in virology under the direction of a member of the graduate faculty. May be repeated for credit.

Permission of the instructor or one prior immunology course. Directed readings in immunology under the direction of a member of the graduate faculty. May be repeated for credit.

Permission of the instructor. This course will provide multiple opportunities for the student to write parts of hypothesis-based proposals, receive substantial feedback, and to rewrite the text. There will be approximately twelve single-page writing assignments.

Permission of the department. Designed to introduce the student to research methods and special techniques. Short-term problems are conducted with the advice and guidance of the staff. May be repeated for credit.