Department of Microbiology and Immunology

Department of Microbiology and Immunology

http://www.med.unc.edu/microimm

125 Mason Farm Road, 6th Floor Marsico Hall, CB# 7290

(919) 966-1191

WILLIAM E. GOLDMAN, Chair

The Department of Microbiology and Immunology is one of the basic science departments of the UNC School of Medicine. Although the department participates actively in the undergraduate curriculum in biology and several of its courses are open to undergraduate students in the College of Arts and Sciences, the department does not offer an undergraduate major in microbiology. MCRO 251 is an undergraduate course specifically designed to serve as the required prerequisite for students applying to pharmacy or nursing programs, although other students with the required science background may take the course. Most of the other courses offered by the department are available to highly motivated undergraduate students with the necessary preparation, although it is important for such students to consult the course instructor before registering.

MCRO–Microbiology

Undergraduate-level Courses

MCRO 50. First-Year Seminar: Infectious Disease in Society. 3 Credits.

Selected aspects of microorganisms that cause infectious diseases, how new infectious diseases emerge, what bioterrorism is and how we are trying to counteract it in the United States, and how changes in the food supply have presented new infectious disease challenges.
Gen Ed: PL.
Grading status: Letter grade.

MCRO 251. Introductory Medical Microbiology. 4 Credits.

Required preparation, one semester of a basic undergraduate science class. An introductory course in microbiology that focuses on the structure, biology, and genetics of microbes in relation to human disease and the immune system. For students planning careers in pharmacy, nursing, dental hygiene, and related fields. A laboratory is required. Students may not receive credit for both MCRO 251 and MCRO 255.
Grading status: Letter grade.

MCRO 255. Elementary Pathogenic Microbiology. 4 Credits.

Required preparation, one semester of a basic undergraduate science class. An introductory course in microbiology that focuses on the structure, biology, and genetics of microbes in relation to human disease and the immune system. For students planning careers in pharmacy, nursing, dental hygiene, and related fields. A laboratory is required. Students may not receive credit for both MCRO 251 and MCRO 255.
Grading status: Letter grade.

Advanced Undergraduate and Graduate-level Courses

MCRO 449. Introduction to Immunology. 3 Credits.

This course provides a general overview of the evolution, organization, and function of the immune system. Instruction will be inquiry-based with extensive use of informational and instructional technology tools.
Requisites: Prerequisite, BIOL 205; permission of the instructor for students lacking the prerequisite.
Grading status: Letter grade
Same as: BIOL 449.

MCRO 515. Introduction to Microbiology. 4 Credits.

Open only to dental students. A course covering basic aspects of microbiology and immunology including sterilization, action of antimicrobial chemotherapeutic agents, concepts of infection and immunity, and the study of certain selected infectious agents.
Grading status: Letter grade.

MCRO 614. Immunobiology. 3 Credits.

A strong background in molecular biology, eukaryotic genetics, and biochemistry is required. Advanced survey course with topics that include molecular recognition, genetic mechanisms of host resistance, development of cells and cell interactions; hypersensitivity, autoimmunity, and resistance to infection. Course material from textbook and primary literature.
Grading status: Letter grade.

MCRO 630. Virology. 3 Credits.

Required preparation, coursework in molecular biology and cell biology. Current concepts of the chemistry, structure, replication, genetics, and the natural history of animal viruses and their host cells.
Grading status: Letter grade.

MCRO 631. Advanced Molecular Biology I. 3 Credits.

Required preparation for undergraduates, at least one undergraduate course in both biochemistry and genetics. DNA structure, function, and interactions in prokaryotic and eukaryotic systems, including chromosome structure, replication, recombination, repair, and genome fluidity. Three lecture hours a week.
Grading status: Letter grade
Same as: GNET 631, BIOC 631, BIOL 631.

MCRO 632. Advanced Molecular Biology II. 3 Credits.

Required preparation for undergraduates, at least one undergraduate course in both biochemistry and genetics. The purpose of this course is to provide historical, basic, and current information about the flow and regulation of genetic information from DNA to RNA in a variety of biological systems. Three lecture hours a week.
Grading status: Letter grade
Same as: GNET 632, BIOC 632, BIOL 632.

MCRO 635. Microbial Pathogenesis I. 3 Credits.

Permission of the instructor. Required preparation, coursework in molecular biology and genetics. Topics will include aspects of basic bacteriology as well as bacterial and fungal pathogens and mechanisms of disease.
Grading status: Letter grade.

MCRO 640. Microbial Pathogenesis II. 3 Credits.

Permission of the instructor or a fundamental understanding of molecular virology and immunology. Molecular pathogenesis, with a primary focus on viral pathogens. Additional topics include vaccines and genetics of host-pathogen interactions.
Grading status: Letter grade.

MCRO 643. Cell Structure, Function, and Growth Control I. 3 Credits.

Comprehensive introduction to cell structure, function, and transformation.
Requisites: Prerequisite, undergraduate cell biology or biochemistry or permission of the instructor.
Grading status: Letter grade
Same as: CBIO 643, BIOC 643, PHCO 643, PHYI 643.

MCRO 644. Cell Structure, Function, and Growth Control II. 3 Credits.

Comprehensive introduction to cell structure, function, and transformation.
Requisites: Prerequisite, undergraduate cell biology or biochemistry or permission of the instructor.
Grading status: Letter grade
Same as: CBIO 644, PHCO 644, BIOC 644, PHYI 644.

MCRO 690. Special Topics in Microbiology or Immunology. 1-15 Credits.

Permission of the department except for department majors. Designed to introduce the student to research methods. Minor investigative problems are conducted with advice and guidance of the staff. Hours and credit to be arranged, any term. May be repeated for credit two or more semesters.
Repeat rules: May be repeated for credit; may be repeated in the same term for different topics; 15 total credits. 5 total completions.
Grading status: Letter grade.